Category Archives: News

New SPP2002 Publications

Reprograming of sRNA target specificity by the leader peptide peTrpL in response to antibiotic exposure Hendrik Melior, Siqi Li, Maximilian Stötzel, Sandra Maaß, Rubina Schütz, Saina Azarderakhsh, Aleksei Shevkoplias, Susanne Barth-Weber, Kathrin Baumgardt, John Ziebuhr, Konrad U Förstner, Zoe Chervontseva, Dörte Becher, Elena Evguenieva-Hackenberg Summary Trans-acting regulatory RNAs have the capacity to base pair with […]

Announcement: Virtual Conference on Prokaryotic Small Proteins, January 12-14, 2021

Virtual Conference on Prokaryotic Small Proteins Link: Small Proteins – Big Questions January 12-14, 2021 15:30 – 19:00 Europe / 9:30 am – 1:00 pm EST A virtual conference focused on the discovery and analysis of small proteins and small ORFs in prokaryotic systems.   The conference will comprise 15-minute presentations by established and rising […]

SPP 2002 paper: “Multidimensional separation schemes enhance the identification and molecular characterization of low molecular weight proteomes and short open reading frame encoded peptides in top-down proteomics”

“Multidimensional separation schemes enhance the identification and molecular characterization of low molecular weight proteomes and short open reading frame encoded peptides in top-down proteomics” Cassidy L*, Helbig AO, Kaulich PT, Weidenbach K, Schmitz RA* & Tholey A* *SPP 2002 members Abstract:Short open reading frame-encoded peptides (SEP) represent a widely undiscovered part of the proteome. The detailed analysis of […]

SPP 2002 paper: “Biological functions, genetic and biochemical characterization, and NMR structure determination of the small zinc finger protein HVO_2753 from Haloferax volcanii”

“Biological functions, genetic and biochemical characterization, and NMR structure determination of the small zinc finger protein HVO_2753 from Haloferax volcanii” Zahn S*, Kubatova N*, Pyper DJ*, Cassidy L*, Saxena K, Tholey A*, Schwalbe H*, Soppa J* *SPP 2002 members Abstract:The genome of the halophilic archaeon Haloferax volcanii encodes more than 40 one-domain zinc finger µ-proteins. Only one of these, HVO_2753, contains four C(P)XCG […]

SPP 2002 paper: “The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics”

“The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics” Schulze S, Adams Z, Cerletti M, De Castro R, Ferreira-Cerca S, Fufezan C, Giménez M I, Hippler M, Jevtic Z, Knüppel R, Legerme G, Lenz C, Marchfelder A*, Maupin-Furlow J, Paggi R A, Pfeiffer F, Poetsch A, Urlaub H & Pohlschroder M *SPP 2002 member Abstract:While many aspects of archaeal cell biology remain relatively unexplored, systems biology approaches like mass spectrometry […]

SPP 2002 paper: “Post-translational insertion of small membrane proteins by the bacterial signal recognition particle”

“Post-translational insertion of small membrane proteins by the bacterial signal recognition particle” Steinberg R*, Origi A*, Natriashvili A*, Sarmah P, Licheva M, Walker P M, Kraft C, High S, Luirink J, Shi W Q, Helmstädter M, Ulbrich M H and Koch HG* *SPP 2002 members Abstract:Small membrane proteins represent a largely unexplored yet abundant class […]

SPP 2002 paper: “Eeyarestatin 24 Impairs SecYEG-dependent Protein Trafficking and Inhibits Growth of Clinically Relevant Pathogens”

“Eeyarestatin 24 Impairs SecYEG-dependent Protein Trafficking and Inhibits Growth of Clinically Relevant Pathogens” Steenhuis M , Koningstein G M, Oswald J, Pick T, O’Keefe S, Koch HG*, Cavalié A, Whitehead R C, Swanton E, High S, Luirink J *SPP 2002 member Abstract:Eeyarestatin 1 (ES1) is an inhibitor of endoplasmic reticulum (ER) associated protein degradation, Sec61-dependent Ca2+ homeostasis and protein translocation into the ER. Recently, evidence was […]

SPP 2002 paper: “AcnSP – A Novel Small Protein Regulator of Aconitase Activity in the Cyanobacterium Synechocystis sp. PCC 6803”

“AcnSP – A Novel Small Protein Regulator of Aconitase Activity in the Cyanobacterium Synechocystis sp. PCC 6803” de Alvarenga L V , Hess W R* and Hagemann M* *SPP 2002 members Abstract:Synechocystis sp. PCC 6803 is a widely used model cyanobacterium whose genome has been well annotated. However, several additional small protein coding sequences (sORFs) have been recently identified, […]